This program studies the biological processes by which the body reproduces cancerous tumors, and summarizes the results of current research. The various steps of metastasis are clearly demonstrated in film and computer animation. A film segment of real human tissue shows tumor cells moving in a regulated manner under the direction of 'leader cells.' Computer animation illustrates how a normal cell becomes cancerous. Treatments under development for the prevention of metastasis in certain cancers are summarized. (39 minutes)